ABSTRACT
Nosocomial infections occur 48-72 hours after hospitalization, especially caused by bacteria, and pose a high risk for patients in intensive care units (ICUs), including COVID-ICUs. This study aimed to reveal bacteria distribution and antibiotic susceptibility profiles isolated from various clinical samples of non-COVID-ICU and COVID-ICU patients. We included in this study bacterial strains isolated from ICUs patients in Kastamonu Training and Research Hospital between March 2020 and October 2020. We identified the strains using the Vitek 2 compact automated system (BioMerieux, France) and standard microbiological methods. Using the Vitek 2 automated system, we analyzed antibiotic susceptibility tests and interpreted the results based on the European Committee for Antimicrobial Susceptibility Tests (EUCAST) guideline. There were 302 patients in the non-COVID-ICUs and 440 patients in the COVID-ICUs. We isolated a total of 470 strains, 370 from non-COVID-ICUs and 100 from COVID-ICUs. Acinetobacter spp. was the most frequently isolated strains for both ICUs. Acinetobacter spp. isolated from non-COVID-ICUs had higher resistance rates to meropenem (p= 0.043), ceftazidime (p= 0.014), and levofloxacin (p<0.001) antibiotics than strains from COVID-ICUs. Antibiotic susceptibility profiles of other strains were similar for both ICUs. As a result, the incidence of nosocomial infections in COVID-ICU patients was lower than in non-COVID-ICU patients. Health personnel working in COVID-ICUs may have played an important role in this, as they were more careful about using personal protective equipment and complying with hygiene rules. However, antibiotic resistance continues to be a serious problem in ICUs, including COVID-ICUs. Copyright © 2022 Ondokuz Mayis Universitesi. All rights reserved.
ABSTRACT
This study was carried out to find out the etiology and predisposing factors of calves having diarrhea from Kayseri province and its neighboring cities between January 2016 and September 2019. A total of 270 neonatal diarrheic calves were included to this study. Comprehensive information was obtained by face-to-face interviews with the animal owners about administrative practices such as the vaccination status of the dams, farm type, colostrum intake status. The etiological agents were determined using the lateral flow immunochromatographic test kits. As a result of this investigation, out of 270 diarrheic cases;21.9% (59) Cryptosporidium spp., 15.6% (42) E. coli K99+, 14.1% (38) bovine coronavirus (BCoV), 10.4% (28) bovine rotavirus (BRV), 9.3% (25) Cryptosporidium spp.+BRV, 8.5% (23) BRV+BCoV were found. Interms of shelter type;85.2% (230) were traditional and 14.8% (40) were modern type. Regarding the colostrum intake situation;7.4% (20) received no colostrum, 11.1% (30) received insufficient colostrum and 81.5% (220) received colostrum adequately and on time. Additionally, 36.7% (99) calf mothers were vaccinated and 63.3% (171) were unvaccinated. Compared to those born in autumn, calves born in winter;6.5-fold, in the spring season;3.6-fold and in summer;5.2-fold more likely to develop diarrhea caused by E. coli K99+. These findings may generate valuable information not only for the clinicians and researchers but also animal health experts, policy makers, farmer etc.